If you're living with intensely itchy, raised bumps on your skin that seem to persist or worsen with scratching, you may be experiencing a condition known as prurigo nodularis. This chronic inflammatory skin disorder can severely impact quality of life due to its relentless itch-scratch cycle.
What Is Prurigo Nodularis?
Prurigo nodularis (PN) is a chronic skin condition characterized by multiple firm, itchy nodules that typically develop on the arms, legs, and trunk. These nodules often appear as a result of long-term scratching or rubbing and can vary in size and appearance. The itching can be intense and persistent, leading to significant discomfort, sleep disturbance, and emotional distress.
Unlike a simple rash, prurigo nodularis involves a complex interaction between the skin and the nervous system, with nerve fibers in the skin playing a central role in symptom development.
What Causes Prurigo Nodularis?
The exact cause of PN isn’t fully understood, but it is often associated with other underlying conditions or triggers such as:
- Chronic skin diseases: Eczema, psoriasis, or lichen simplex chronicus.
- Systemic conditions: Kidney disease, liver dysfunction, or thyroid disorders.
- Neurological factors: Altered nerve responses or neurogenic inflammation.
- Mental health concerns: Anxiety, depression, or obsessive scratching behavior.
- External irritants: Insect bites or other trauma to the skin.
In many cases, the condition is considered idiopathic, meaning no clear underlying cause is identified.
Symptoms of Prurigo Nodularis
Common signs and symptoms include:
- Intensely itchy, firm bumps or nodules on the skin
- Lesions commonly located on the arms, legs, and upper back
- Nodules may become scaly, crusted, or scarred
- Skin thickening (lichenification) from repeated scratching
- Sleep disruption or mood changes due to persistent itching
How Is It Diagnosed?
Diagnosis typically begins with a thorough physical examination and discussion of your symptoms. Your dermatologist will evaluate the appearance and distribution of the nodules and ask about your medical history, including any chronic conditions or medications.
In some cases, a skin biopsy may be performed to rule out other possible skin diseases and confirm the diagnosis of prurigo nodularis. Blood tests may also be recommended to identify underlying systemic causes.
Treatment Options for Prurigo Nodularis
Managing PN often requires a comprehensive approach to reduce itching, heal the skin, and prevent further damage. Treatment options include:
- Topical corticosteroids: Help reduce inflammation and itching.
- Antihistamines: May provide some itch relief, especially at night.
- Phototherapy: Controlled exposure to ultraviolet light can be effective for stubborn cases.
- Cryotherapy: Freezing nodules with liquid nitrogen to promote resolution.
- Immunomodulating medications: Such as topical calcineurin inhibitors or systemic therapies in severe cases.
- Biologic treatments: In select cases, newer targeted therapies may be prescribed to reduce immune-driven inflammation.
- Behavioral support: Addressing the psychological components of itching and scratching.
At Brilliance Dermatology, our team tailors your treatment plan based on the severity of your condition and any underlying medical concerns. With extensive experience and a commitment to compassionate care, we help you break the itch-scratch cycle for long-term relief.
Contact Us Today!
23501 Park Sorrento #216 Calabasas, CA 91302
1000 Newbury Rd. #180,Thousand Oaks, CA 91320
Contact© Brilliance Dermatology. Alternate Phone: (818) 222-7495
All Rights Reserved. Web Design & Internet Marketing by Studio III